Searchable abstracts of presentations at key conferences in endocrinology

ea0063p732 | Pituitary and Neuroendocrinology 2 | ECE2019

Assessing clinical meaningfulness of quality of life (qol) change in patients with Cushing’s disease: calculation of minimal important difference estimates for the cushingqol using anchor and distribution-based approaches

Wu Ying , Brohan Elaine , Sully Kate , Maamari Ricardo

Purpose: Patients with Cushing’s disease (CD) experience a wide range of physical and psychosocial health impacts. This can have a profound effect on patient’s quality of life (QOL), impairing areas such as body image, personal relationships and work performance. The CushingQoL is a valid and reliable disease-specific patient-reported outcome (PRO). When using a PRO in an interventional context it is critical to understand whether reported change is clinically meanin...